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Exploitable Innovations

  • Decision Aid for prostate cancer patients

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The purpose of this Decision Aid is to assist men with early-stage prostate cancer in making a treatment decision. Prostate cancer patients are guided through pros and cons of the choice prior to consultation. At the end of the decision aid, patients can write up a list of questions to ask during consultation. Lists of important questions to a particular diagnosis or treatment situations could be created (e.g., questions around prostatectomy or radiotherapy, etc.)

This information can be provided to the clinician in order to guide consultation based on themes that are relevant for the patient and to his family. Expected outcomes from using the decision aid would be greater information comprehension, increased satisfaction with the consultation, greater choice satisfaction (i.e., reduced regret), and eventually higher empowerment and self-management abilities.

Furthermore, the information provided by the Decision Aid could be combined with patient information about his family, and with the patient profile provided by the Psycho-emotional monitoring questionnaire.


  • Serious Game for the encouragement of self-efficacy of children and adolescents patients with cancer

A serious game for children and adolescents for use beside the cancer therapy to encourage self-efficacy of the young cancer patients. The innovation will be available as an app ready for Android and iOS and includes two different games, a shooter game for the children and a match 3 game for an older target group (like grandparents). The game includes an asynchronous multiplayer which allows family and friends to support the children with cancer by playing for them and sending them gifts, which they got as game rewards.


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  • Personal Health Record – iPHR

Over the last 20 years personal health record systems have faced many challenges due to issues of trust, lack of interoperability, and limited usefulness to the patient. The iManageCancer Personal Health Record system, (iPHR), has been developed to address these challenges. The system helps empower patients through self-management, allowing them to involve all stakeholders involved in their care including family and informal carers if they choose.

With iPHR patients can monitor their health in real time, better manage their treatment at home, and choose to share their data with their healthcare professionals, informal carers and supporters for better tailored care and outcomes. As iPHR is open source, patients own their personal health record. Using their own iPHR they can search for personalised and verified information; use treatment decision tools; have the ability to record day to day experiences such as side effects and non-prescription medication; as well as tools for psycho-emotional monitoring; environmental, lifestyle and dietary habits providing the patient with a complete overview of their health.

The open source software of tools developed for iPHR include nine applications created for patients (e-Diary, Appointments, problems, medications, measurements, psycho-emotional monitoring, contact, documents repository, e-Consent and information recommender) and three applications for clinicians (annotator for the information recommender, psycho-emotional profiler and smart analytics).

These components are available open source for developers wishing to apply them to various domains within biomedical informatics, at the following public repository:

iPHR Server:

https://github.com/Chatzimina/indivo_server

iPHR GUI:

https://github.com/Chatzimina/indivo_ui_server

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Read more


  • Clinical decision support and disease management framework - Care Flow Engine

The tools and services developed have been seen by patients and clinicians as having huge potential for collecting and managing reports from patients on outcome and experiences, and also in guiding clinicians through clinical pathways and clinical trial outlines for their patients with the aim to save resources, detect health deteriorations earlier and avoid unnecessary clinical procedures.

Patient reported outcome measures (PROMs) and patient reported experience measures (PREMs) are increasingly being recognized as important for assessing quality of healthcare, evaluating outcomes of specific interventions and for clinical assessment and decision support.

With the Care Flow Engine technology, report forms for a particular use like long-term follow up can be created on the fly and made available to patients for reporting, while the system itself can analyse the answers and guide clinicians and patients through different paths of the Care Flow. In addition, in the context of drug management with the iManageMyHealth app, patients can already report on side effects and outcome, however, a more structured reporting is required than just free text in order to analyse the reports, detect abnormal health states and propose the right interventions by the system. The corresponding knowledge can be modelled in the Care Flow Engine for improved monitoring of PROMs and PREMs.


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  • Serious game for adults

The game’s purpose is to help patients view their disease fight from a new perspective as well as provide a fun and challenging activity. It does this in a number of different ways:

Help a patient and their relatives deal with the psychological dimensions of their disease

The game is designed to promote a positive message of “well being can be achieved through good management” while allowing a basic social avatar sharing mechanic for friends and family.

Disease fight in a different perspective

The game puts the user in the role of a supportive mayor character helping his citizens with cancer. This change in role is intended to allow users to think about cancer from other’s perspective.

Promote disease management

The game rewards time and lifestyle balancing, this is intended to make a user think more critically about their own time management

Encourage healthy habits

The game weights healthy activities to provide more balanced and useful stat changes, while also suggesting that some activities can have positive effects

Reduce stress, anxiety related to negative impact of their disease

The game is intended to provide a distraction from their specific illness while still focusing on cancer as whole.

Enhance patient’s knowledge

The game has a trivia mini-game embedded within each building, completing this grants discounts at theta building.

The trivia is general lifestyle and general knowledge.

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  • MyHealthAvatar apps for prostate and breast cancer

Two android apps have been developed for prostate and breast cancer patients. Each app is tailored to the specific information needs of prostate and breast cancer patients to support them in managing their well-being. MyHealthAvatar, (MHA), collects and analyses lifestyle and health data, providing visual analytics which contributes to individualized disease prediction and prevention, and supports healthy lifestyles and independent living. The apps offer a range of functionalities:

Information Collection and Access

Mobile based GPS and sensors are used in data collection and information access.

MHA stores the individual patient avatar data in the iPHR repository where it is accessible to the patient and doctors

Data Management and Sharing

MHA is a tool that allows highly self-motivated data management and user-centred data collection, supported by the necessary data integrity measures.

The patients have full rights over sharing their own data.

Information Analysis and Visual Analysis

The purpose of health and medical information collection is to promote healthy lifestyles of patients and to assist clinical decision making.

Doctors can make basic analyses based on knowledge from the platform and augment their clinical knowledge with heterogeneous information from the avatar.

Health Questionnaire and Exercise Information

To help patients’ recovery and lower the risk after surgery, the apps offer health questionnaires and exercise suggestions for the patients.

According to the result of the questionnaires, the patients can do a self-check for their health status which can inform their consultation with doctors.

Cancer Knowledge

To raise the patients’ risk awareness, the MHA app provides the function to improve the patients’ knowledge about health and diseases by tailored information provision.

Visualization and visual analysis are critical parts for the effective utilisation of data collected and stored on the MHA platform.

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  • Environment for the description, storage, testing, and management of knowledge models

A scalable environment comprising of a repository and a set of services enabling the standardized description, storage, testing/execution, and management of knowledge models to support their deployment and reuse by a wide community.


  • Creation of a pre-treatment model to predict febrile neutropenia risk in cancer patients

A predictive model that enables febrile neutropenia risk profiling in cancer patients before the start of the treatment to help avoid chemotherapy complications. It aims to increase treatment safety and improve the efficiency of resource use.